



Low thyroid function, whether overt or subclinical, has become one of the most common health problems in the developed world today. While there are many contributing factors, some commonly identified risk factors include poor diet, excessive stress, and polypharmacy. Thyroid Matrix BA is a blend of nutrients designed to address all of these factors and improve and optimize thyroid function.
L-tyrosine is the amino acid that makes up thyroid hormones. It's the same amino acid needed to produce cortisol, our anti-stress hormone, and neurotransmitters such as dopamine, norepinephrine, and epinephrine. Studies show it can improve cognition during times of stress caused by sleep deprivation, cold exposure, combat training, and unpleasant background noise. The inclusion of L-tyrosine in Thyroid Matrix BA is essential for dual thyroid and adrenal care.
When it comes to minerals, selenium is crucial for the proper conversion of the less active thyroid hormone, thyroxine (T4), into the metabolically active triiodothyronine (T3). Without selenium, the metabolically inactive reverse T3 (rT3) is created instead, putting our bodies in a metabolically disadvantageous state. Zinc, iodine, manganese, and copper are also necessary for proper thyroid hormone production, while zinc is also particularly important for increasing thyroid receptor sensitivity. All of these minerals are found in highly bioavailable forms, fully chelated with glycine for optimal stability and absorption.
When it comes to vitamins, vitamin A is an interesting nutrient that appears to work synergistically with iodine to regulate thyroid health, while directly improving thyroid hormone transport and receptors on target tissues. In animals, vitamin A deficiency leads to reduced thyroid hormone synthesis and thyroid enlargement due to decreased iodine absorption. In children with even mild vitamin A deficiency, elevated TSH and less active T4 hormone have been observed. Interestingly, in iodide-deficient children, vitamin A supplementation led not only to improved iodide efficacy, but also to reduced TSH and a lower risk of hypothyroidism. Vitamin B12 is another important vitamin in some patients with thyroid problems, commonly deficient in up to 55% of patients with autoimmune thyroid disease, possibly due to low stomach acid, malabsorption, or even autoimmune gastritis.
Finally, we have plant extracts such as Bacopa monnieri and KSM-66® Withania somnifera that may have a positive impact on the course of thyroid dysfunction. Bacopa is traditionally known for its ability to improve cognition and other areas of neurological function, but animal studies have suggested that it can significantly increase T4 concentrations. Additionally, bacopa has been shown to lower cortisol levels. Poor cognition and unbalanced cortisol levels are associated with thyroid dysfunction. KSM-66® Withania somnifera is also best known for its adaptogenic properties and ability to improve performance during times of stress. However, ashwagandha is a unique adaptogenic herb in that it has a specific affinity for supporting thyroid function, with various studies showing increased thyroid hormone secretion, increased TSH and T4 concentrations.
Collectively, all of these ingredients in Thyroid Matrix BA support thyroid and thyroid hormone health on multiple levels, allowing for a comprehensive and effective approach to an under-functioning thyroid. Thyroid Matrix BA with Bacopa can be considered a more robust formula compared to Thyroid Matrix as it contains the addition of vitamins A, B12, Bacopa monnieri and a higher dosage of Withania somnifera with a higher percentage of withanolide standardization (5% and 1.5%, respectively).