



Testosterone Matrix contains KSM-66® ashwagandha, a proprietary full-spectrum extract of the withania root that has been extensively clinically researched for its use in stress-related health issues. Through a patented alcohol- and solvent-free extraction process that took over a decade to develop, KSM-66® is able to retain high concentrations of both hydrophilic and lipophilic components of the raw root. KSM-66® is unique compared to other ashwagandha root extracts because it has been specifically studied and shown to improve sperm parameters, muscle strength, testosterone levels in men, and sexual function in women. KSM-66® has also undergone over 20 human clinical trials to support its effectiveness in the areas of memory and cognition, stress reduction, improved thyroid function, and weight management.
Trigonella foenum-graecum, better known as fenugreek, has traditionally been used to increase milk production in breastfeeding women and as an effective tool for regulating blood sugar levels. More recent data has shown that a particular fenugreek extract known as Testofen®, which is standardized to a proprietary blend of saponin glycosides, may promote healthy testosterone levels in men. A double-blind, placebo-controlled clinical trial in resistance-training men aged 18 to 35 showed a significant increase in total and free testosterone, by 11% and 99%, respectively, after 8 weeks of supplementation. Another double-blind, placebo-controlled human study used Testofen® in combination with magnesium, zinc, and vitamin B6 for 6 weeks and found significant improvements in the self-assessed areas of sexual arousal, orgasm, libido, quality of sexual performance, energy, and overall well-being. A third trial involving 120 men aged 43 to 70 confirmed that treatment with Testofen® as monotherapy can effectively reduce the normal symptoms of andropause and improve sexual health by significantly increasing sexual arousal, desire, and activity, as well as free and total testosterone levels.
Finally, certain nutrients have been shown to support endogenous testosterone production. Zinc's reputation as an immune-boosting mineral is well-deserved, but it is highly recommended for healthy hormonal support. In particular, zinc deficiency in men can negatively affect sperm parameters, and it is one of the few nutrients shown to contribute to low testosterone. Additionally, zinc supplementation has been shown to increase free testosterone levels in men with suboptimal baseline levels and may improve mood and cognition by increasing brain-derived neurotrophic factor and blocking NMDA receptors in the brain.
Vitamin D is the other key nutrient that plays a role in testosterone regulation. Although more research is needed to determine the exact relationship, serum vitamin D concentrations have been shown to be a significant and positive predictor of total testosterone levels in several observational trials. This correlation has also been observed in women. Additionally, one interventional trial showed that vitamin D supplementation helped increase testosterone levels in men who were vitamin D deficient at baseline.
Overall, Testosterone Matrix has been formulated to provide evidence-based dosages of KSM-66® ashwagandha and Testofen® fenugreek, along with supportive vitamins and minerals, to optimally support healthy testosterone levels, strength, libido, and cognition in men.