Sleep Matrix Melatonin

• A formula designed to target multiple factors that contribute to insomnia, resulting in reduced sleep latency, fewer awakenings, and better sleep quality
• Melatonin resets the circadian rhythm and is particularly indicated for shift workers or people wishing to avoid jet lag, capable of improving all sleep parameters
• Nerve plant extracts of Valeriana officianalis, Passiflora incarnata and Melissa officinalis are included to positively modulate the body's stress response and calm the nervous system
• The amino acids, GABA and L-theanine, help act as inhibitory neurotransmitters that reduce nervous system excitability, increase alpha brain waves, and decrease the time it takes to fall asleep.
  

Poor sleep quality is experienced by more than one in three adults at some point in their lives, with the prevalence and severity only increasing with age. Many of these individuals resort to over-the-counter medications, pharmaceuticals, alcohol, or other substances to improve their problematic sleep. Unfortunately, these substances may simply contribute to the growing list of chronic health conditions already linked to ongoing sleep problems, such as heart disease, impaired immunity, metabolic dysfunction, and even low bone mineral density. Sleep-Matrix Melatonin offers an effective and natural solution to your patient's sleep problems.

Melatonin is the hormone that regulates our circadian rhythm, the cycle that dictates when we should be awake and when we should be asleep. It is produced naturally in the pineal gland and has well-established benefits as a sleep-aid supplement. Clinical trials have shown that melatonin can reduce the time it takes to fall asleep and improve the ability to stay asleep, thereby increasing total sleep time and rest. Melatonin is particularly indicated for people who work irregular day and night shifts or to prevent jet lag in people who travel frequently.

Various herbal extracts can support the use of melatonin and also support sleep parameters. One of the best-studied herbs for insomnia is Valeriana officianalis, commonly known as valerian root. In vitro data have shown that valerian root can stimulate the release of gamma-aminobutyric acid (GABA) in the brain and simultaneously block its reuptake. This may explain why valerian root showed comparable efficacy to a benzodiazepine medication for sleep quality after a 4-week intervention, but with fewer side effects. A meta-analysis examined 16 studies of valerian root on sleep quality, finding a relative improvement in sleep markers of 80% compared to placebo in a subset of trials.

Passiflora incarnata and Melissa officinalis are two other calming herbs that stimulate GABA receptors and positively regulate stress, respectively. Studies examining Passiflora incarnata have shown that even just 7 days of consumption in tea form can improve sleep parameters, and its supplementation can significantly reduce stress. Finally, Scutellaria lateriflorais is included for its nervine effects and activation of GABA receptors, mainly due to the active ingredient baicalin.

In addition to melatonin and herbal extracts, amino acids may play a positive role in relieving insomnia. GABA is a well-known inhibitory neurotransmitter that has been found to relax the mind and reduce the time it takes to fall asleep. Similarly, L-theanine is a unique amino acid, naturally found in green tea, which is well known to calm the mind and improve concentration. Research has shown that L-theanine can increase levels of various neurotransmitters in the brain, such as serotonin, dopamine, and GABA, while blocking excitatory glutamate receptors. Ultimately, L-theanine increases alpha brain waves and improves stress markers such as heart rate, blood pressure, and salivary immunoglobulin A.

Each of these aforementioned ingredients is included in Sleep-Matrix Melatonin to address several possible causes of poor sleep in people suffering from insomnia. Sleep-Matrix Melatonin is an evidence-based blend indicated to increase sleep latency, duration, and quality. 60 vegetarian capsules per bottle.