



S-adenosyl-L-methionine (SAMe) is a naturally occurring compound and methyl group donor that supports the methylation cycle, a metabolic process essential for many aspects of health. Methylation is essential for ridding the body of certain toxins, and it is also important for some people, such as those with chronic liver disease, who cannot produce adequate levels of SAMe.
The effectiveness of SAMe in supporting a balanced mood has been demonstrated by numerous clinical studies. In fact, SAMe is so effective in boosting depression that it is legally registered as a prescription medication in several European countries for mood balance. One study also demonstrated the effectiveness of SAMe taken as a common prescription medication for mood. SAMe is believed to work by boosting serotonin, dopamine, and melatonin levels in the brain, where low levels of these substances are commonly associated with mood imbalances such as anxiety and depression. SAMe has also been found to promote joint health in osteoarthritis patients as effectively as a well-known anti-inflammatory, reducing inflammation and protecting joint tissue from degradation.
AOR's SAMe 400 provides an effective dose and stable form of this valuable compound in an enteric-coated tablet for maximum effectiveness. The first SAMe supplement was introduced by AOR in Canada in 2000.