



Quercetin + Nettle provides 600 mg of quercetin and 600 mg of nettle per three-capsule serving. This targeted and highly effective combination of ingredients helps modulate inflammation and immune responses in conditions that have an inflammatory etiopathogenesis such as allergic rhinitis, asthma, eosinophilia, inflammatory bowel disease, osteoarthritis, obesity, type II diabetes, and even some cancers. Research suggests that the anti-inflammatory, antioxidant, and antiviral properties of nettle and quercetin are mediated by their ability to disrupt the production and actions of pro-inflammatory mediators such as cytokines, leukotrienes, prostaglandins, and interleukins.
Quercetin, also known as the “queen of flavonoids,” is considered one of the best plant-derived phenolic compounds due to its powerful antioxidant properties and ability to support a healthy inflammatory response in the body. Quercetin is a powerful flavonol found in many foods known for their health benefits, such as red onions, apples, olive oil, dark berries and grapes, capers, broccoli, and culinary greens and herbs such as dill, cilantro, watercress, and radicchio (quercetin contributes to the richly colored pigments in these foods). Recent genomic research has shown that by binding to DNA or other proteins, quercetin acts as a cis-regulatory transcription factor that modulates the expression of genes involved in the cell cycle, differentiation, and development. Furthermore, this phenolic compound demonstrates an ability to attenuate lipid peroxidation, capillary permeability and platelet aggregation.
The nettle plant (Urtica dioica L.) has traditionally been used throughout the world as a folk medicinal remedy to support respiratory and joint health, but also in various other applications such as hypertension. 11 Its use is documented in ancient Egypt and Greece as well as among the indigenous peoples of North America; it can be consumed directly or made into soups, tea, and even beer. Nettle has a very high content of vitamin C and iron, nutrients that underlie its role in the immune response as a potent antioxidant, anti-inflammatory, and antihistamine agent.