PQQ and CoQ10 are synergistic nutrients that modulate cellular signaling pathways, neutralize reactive oxygen species, and promote optimal mitochondrial function. Mitochondrial dysfunction and oxidative stress are implicated in a growing number of conditions and are thought to play an important role in egg and sperm quality, as well as cellular aging. CoQ10 is well established as a mitochondrial stimulant, with proven benefits in the treatment and prevention of numerous cardiovascular and neurological conditions. CoQ10 also affects oocyte mitochondrial function, sperm quality, and fertility. CoQ10 increases the efficiency of mitochondrial ATP production and cellular respiration.
PQQ is a novel biofactor known to influence multiple cellular pathways, including the production of nerve growth factor (NGF). PQQ has various benefits for mitochondrial function and has been shown to attenuate mitochondrial oxidative stress and stimulate mitochondrial biogenesis. It also has neuroprotective properties, including protection against glutamate-induced toxicity, a pathway common to many neurodegenerative diseases. BioPQQ is considered a novel cofactor with antioxidant and vitamin B-like activity. It is naturally fermented to improve vitamin B absorption and make it more effective. It is naturally fermented to improve vitamin B absorption.
Together, PQQ and CoQ10 have shown clinical benefits for improving cognitive performance such as attention and information processing, cardiovascular health, and providing superior mitochondrial support.