OA Matrix

• Indicated to reduce the symptoms of osteoarthritis, protect joints from further damage, and reduce the need for prescription or over-the-counter pain relievers and anti-inflammatory agents
• Contains a blend of glucosamine sulfate, chondroitin sulfate, and methylsulfonylmethane (MSM) to collectively improve the production of articular cartilage and synovial fluid in joints
• Turmeric root is supplied as a highly standardized and well-researched C3 complex, providing a minimum curcuminoid content of 95%.
• Boswellia serrata is standardized to contain 70% boswellic acid, a very potent amount of active ingredient for inflammation and joint protection.

Osteoarthritis (OA) is the most common form of joint pain that becomes increasingly prevalent as we age, partly due to excessive wear and tear on the body. With progressive erosion of joint cartilage and resulting inflammation, people with OA experience pain, reduced range of motion, and increased stiffness, all of which can have a significant impact on their quality of life.

There are many natural agents that can be used to improve outcomes in patients with osteoarthritis, but few have more research and years of clinical support than glucosamine, chondroitin, and methylsulfonylmethane (MSM). These agents are all basic components of cartilage and synovial fluid, helping to provide shock absorption to the joint and reduce friction with movement. For example, glucosamine is naturally produced by chondrocytes and is necessary to make glycosaminoglycans, a central component of cartilage, and hyaluronic acid, a central component of synovial fluid. Glucosamine sulfate, in particular, stimulates the anabolic process of cartilage metabolism and improves clinical outcomes more effectively than glucosamine hydrochloride.

While each of these nutrients has its own role in improving joint health and reducing symptomatic markers, combination therapies with these natural agents tend to provide better clinical and research results compared to monotherapy. Additionally, many natural health supplements claimed to improve joint health provide inadequate dosages to provide benefits, so it is important to ensure evidence-based daily intakes when evaluating products.

While structural nutrients undoubtedly play a role in managing osteoarthritis, there are also powerful natural anti-inflammatory herbs such as Curcuma longa and Boswellia serrata that should be considered. In both cases, several human clinical trials have confirmed that these herbs can be beneficial for people with osteoarthritis and rheumatoid arthritis.

Curcuma longa contains active ingredients known as curcuminoids, which have been shown to inhibit NF-kappa B and TNF-alpha in chronic inflammatory conditions. Research trials have shown that curcuminoids can reduce the need for pain medications such as acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) in people with osteoarthritis, and also reduce muscle soreness after exercise. In addition to their anti-inflammatory action on NF-kappa B and TNF-alpha, curcuminoids inhibit matrix metalloproteinase-3, an enzyme known to break down cartilage. This means that it not only improves symptoms but also protects joints from further damage.

Boswellia's clinical benefits for osteoarthritis appear to stem from its boswellic acid content and its ability to inhibit not only matrix metalloproteinase-3 but also 5-lipoxygenase (5-LOX). Standardized boswellia extracts have shown that the herb can decrease pain, reduce swelling, and increase range of motion. One trial found boswellia to be as effective as the NSAID valdecoxib in relieving osteoarthritis symptoms.

OA.Matrix contains a blend of these 5 evidence-based nutrients and herbs to reduce symptoms in people with osteoarthritis, protect the joint from further damage, and reduce the need for anti-inflammatory pharmaceutical medications. OA.Matrix provides evidence-based doses and standardized extracts for superior clinical outcomes in your patients suffering from joint pain and cartilage degradation.