Methylfolate PlusTM provides folate in the active form of (6S)-5-methyltetrahydrofolic acid, glucosamine salt. Methylfolate is a highly absorbable and activated form of folate, which does not require enzymatic conversion to 5-methylfolate in the body. The glucosamine salt form used in Methylfolate PlusTM is more stable than other commonly used forms of methylfolate. Folate deficiency is one of the most common vitamin deficiencies. In individuals with a homozygous (TT) or heterozygous (CT) genetic predisposition, consuming folate-rich foods may not provide the recommended daily intake of folate, thus the need for supplementation. By directly providing 5-methylfolate, Methylfolate PlusTM may have benefits for those who do not produce enough 5-methylfolate in response to folic acid supplementation. Each serving (1⁄2 tablet) of Methylfolate PlusTM provides 400 mcg of folate as 5-methylfolate, combined with 25 mcg of vitamin B12 as methylcobalamin in our biologically active, phytochemical-rich plant base.