



Cardiovascular disease is one of the leading causes of death in Canada and is often referred to as a "silent killer" due to the lack of symptoms during the disease's progression. However, important cardiovascular risk factors have been identified, such as unbalanced cholesterol levels, elevated triglycerides, and excess homocysteine. In addition to a healthy diet and regular exercise, specific nutrients and herbal extracts are beneficial in supporting these markers and a healthy cardiovascular system.
Policosanol is a mixture of long-chain saturated alcohols derived from the waxes of plants such as sugarcane and yams. The beneficial effects of policosanol on cholesterol have been explored in dozens of human clinical trials and have been shown to lower total cholesterol, reduce low-density lipoprotein (LDL), and increase high-density lipoprotein (HDL), without significant effects on triglyceride levels. Policosanol is ultimately a safe and well-tolerated option for lipid balancing, even in populations with high concomitant medication use.
Guggulsterones are the active medicinal component found in the gum resin of the mukul myrrh tree. Guggulsterones have been shown to effectively lower triglyceride levels by 10 to 20 percent, in addition to reducing total cholesterol levels. In fact, research has shown that guggulsterones are as effective as the prescription drug clofibrate in lowering blood cholesterol and triglyceride levels. Guggulsterone supplementation has also been shown to reduce inflammation in the body, as indicated by lower levels of C-reactive protein.
Red yeast rice contains several compounds collectively known as monacolins, substances known to inhibit HMG-CoA reductase and cholesterol synthesis. However, red yeast rice also contains other active ingredients with beneficial effects on cholesterol. For example, monascin and ankaflavin have been associated with a reduction in total cholesterol, LDL, and triglycerides independent of monacolins through increased cholesterol excretion in the blood and digestive tract. Overall, red yeast rice extracts have been the subject of numerous clinical trials to support the reduction of total and LDL cholesterol levels in the blood.
Homocysteine is a normal metabolite of the methionine cycle, but elevated levels of this metabolite can increase the risk of cardiovascular damage. Hyperhomocysteinemia negatively affects endothelial function, vascular smooth muscle cells, connective tissue, coagulation factors, and platelets. For this reason, it is important to effectively promote the recycling of homocysteine into methionine or its conversion to cysteine. This is achieved by ensuring adequate levels of folate, vitamin B6, vitamin B12, and trimethylglycine.
Inositol hexanicotinate, also known as vitamin B3, is another B vitamin with beneficial effects on the cardiovascular system.
system. Inositol hexanicotinate differs from other forms of vitamin B3 such as nicotinic acid in that it does not cause a typical "flushing" reaction of the skin due to vasodilation.
Cyto-Matrix Lipo-Matrix offers an evidence-based blend of these botanical extracts and nutrients to aid in the overall management of cardiovascular health.