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Glutamine is the most abundant free amino acid in the body, comprising approximately 40–60% of the total amino acid pool in tissues. It is required to perform a variety of essential functions, as it is a necessary substrate for protein synthesis, hepatic ureogenesis, and hepatic and renal gluconeogenesis. It also acts as an anabolic precursor in muscle growth, as a buffer for acid-base balance in the kidneys, as an oxidative fuel for intestinal and immune cells, as a nitrogen transporter between organs, and as a precursor for the synthesis of neurotransmitters, nucleotides, nucleic acids, and glutathione.
Often referred to as the "multitasker," glutamine is a nutrient with an impressive array of health benefits. It helps build lean muscle mass and strengthen the body's defenses. In the gut, it promotes the health and function of lining cells for normal healing and repair. Additionally, glutamine freely distributes nitrogen to the cells that need it most, such as immune, intestinal, and muscle cells.
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