



Iron continues to be the most obvious nutrient deficiency in the developed world, with a particularly high prevalence among women and during pregnancy. In fact, 1 in 2 women will be iron deficient at some point in their lives, and even more will suffer from symptoms associated with suboptimal iron levels. While fatigue, weakness, hair loss, and pallor are classic symptoms of iron deficiency anemia, low iron levels affect many other body systems.
For example, iron deficiency has been found to be a common cause of restless legs syndrome in about 1 in 4 cases, and iron supplementation can improve symptoms. This is thought to be achieved by iron's upregulation of dopamine synthesis from tyrosine. It is also well documented that children and adults perform worse on tests of mental function in iron-deficient states, with areas such as attention, memory, and concentration being affected.
Iron also plays a critical role in many hormonal pathways. Iron is required for the thyroid's conversion of thyroxine (T4) to triiodothyronine (T3), and in hypothyroidism with concomitant iron deficiency, combined treatment with iron and levothyroxine has been shown to be superior to either treatment alone. In women with heavy menstrual bleeding, iron deficiency may actually cause recurrent heavy menstrual bleeding by weakening the uterine muscles, thereby worsening the condition. Evidence also shows that women with unexplained infertility and suboptimal iron status may benefit from iron replacement therapy.
Finally, iron is necessary for proper immune function through the production of cytokines in macrophages, and iron deficiency can lead to an inadequate immune response. For example, research in people with oral thrush has shown that iron restoration can reduce the number of salivary thrush infections and reduce oral lesions.
Despite all the health benefits of targeted iron supplementation, many women and iron-deficient individuals are reluctant to take iron supplements or become noncompliant due to digestive side effects such as constipation, nausea, and stomach upset.
Cyto-Matrix's iron matrix contains iron in a chelated, bisglycinate form, optimal for absorption and gentle action on the digestive tract. This significantly reduces the likelihood of unwanted complications during iron supplementation. Each capsule contains 20 mg of elemental iron with additional vitamins C, B6, B12, folic acid, magnesium, and copper to aid in the absorption of iron from the digestive tract and support the production of healthy red blood cells.