Enhanced B Complex

• Supports energy production, nutrient metabolism, liver function, immune function, and red blood cell production.
• Contributes to healthy hair, skin and nails
• Contains a full spectrum of B vitamins in the most metabolically active forms, which do not require conversion by the liver for utilization.
• Provides a clinically effective dose of the most active and bioavailable form of folate, Quatrefolic.
• Each capsule also provides the most bioactive and bioavailable forms of each B vitamin, including methylcobalamin (B12), riboflavin 5'-phosphate (B2), and pyridoxal 5'-phosphate (B6).
• Suitable for vegetarians and vegans

Bioclinic Naturals Enhanced B Complex is a once-daily formula that provides full-spectrum B vitamins in their most metabolically active forms. B vitamins are cofactors for many important body processes, including nutrient metabolism, energy production, growth and development, and liver function. B vitamins also contribute to immunity, red blood cell production, and iron metabolism, as well as healthy skin, hair, and nails. This formula contains active B vitamins, such as vitamins B12 (methylcobalamin) and B6 (pyridoxal 5'-phosphate), to support nervous system function. It also contains 50 mg of choline and 400 mcg of folate (Quatrefolic). In addition, this formula contains vitamins B1, B2, B5, and B6, plus niacin, with the added support of biotin and inositol. This convenient all-in-one B complex is an ideal supplement to help support metabolism, energy, and overall health.

Quatrefolic acid is a cellularly active form of folate, the form found in the circulation and the only one to cross the blood-brain barrier. It may also be the optimal form for preventing neural tube defects. It does not need to be converted to the active form by the enzyme methylenetetrahydrofolate reductase (MTHFR), which is known to have common single-nucleotide polymorphisms. Administration of quatrefolic acid has been associated with higher peak levels of (6S)-5-MTHF than folic acid and calcium 5-MTHF, even in individuals with high-functioning MTHFR polymorphisms.

Methylcobalamin is a cofactor for B12-dependent enzymes and has direct biological activity. When combined with other B vitamins, it reduces the risk of macular degeneration and migraines, with efficacy sometimes modulated by MTHFR status.