Digest-ProGD HP

• Provides fungal and bacterial proteases to hydrolyze difficult-to-digest proline-containing peptides, such as gluten and casein.
• Provides broad spectrum carbohydrate digestion with plant-derived papain, bromelain, and fungal digestive enzymes.
• The high-potency formulation allows for easy dosing, with nearly 300 mg of enzyme blend in each vegetarian capsule.
• Perfectly suitable for vegetarians and vegans

Digest-ProGD HP is a high-potency, patented enzyme blend for complete carbohydrate digestion. It contains fungal proteases derived from Aspergillus oryzae, bacterial proteases from Bacillus subtilis, and comprehensive carbohydrate digestion support with papain, bromelain, and fungal digestive enzymes. Aspergillus oryzae extracts are rich in prolyl endopeptidases and dipeptidyl peptidase IV (DPP-IV)—a multifunctional serine protease that targets proline-containing peptides, such as those found in gliadin and casein, two proteins resistant to proteolysis.

Indeed, the protease activity of Aspergillus oryzae targets the proline-rich 33-mer of gliadin, perhaps the most immunotoxic peptide derived from gliadin. The proline-rich antigenic and immunomodulatory proteins in gluten are thought to trigger an inflammatory response in patients with celiac disease or gluten sensitivity, often due to accidental gluten exposure, even in individuals on a gluten-free diet. Supplementation with Aspergillus oryzae protease has also been associated with a bifidogenic effect in animals, suggesting a potential probiotic effect, as well as an increase in gut-protective amino acids.

In addition to fungal and bacterial proteases, Digest-ProGD HP provides alpha-amylase, cellulose, and hemicellulose for comprehensive carbohydrate digestion support.