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Curcumin, the primary curcuminoid in turmeric, has been the subject of extensive research in recent years. The pleiotropic nature of curcumin's biological effects makes it an attractive compound for researchers studying common chronic health problems, such as those associated with joints, the cardiovascular system, glucose metabolism, brain function, mood, and cell cycle regulation.
The mechanisms underlying curcumin's effects are diverse and have not been fully elucidated, but curcumin is known to have potent antioxidant activity and multiple molecular targets, including transcription factors, cell cycle proteins, cytokines, chemokines, enzymes (e.g., COX-2), receptors, and adhesion molecules. These effects make curcumin applicable to a wide range of clinical presentations.
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