C Matrix Kids + Elderberry Chewable Tablets

• A standardized, potent elderberry extract with added vitamin C to support immune function in children.
• Designed to gently but effectively support immune function in children and adolescents.
• Contains a highly potent extract of Sambucus nigra, processed without the use of solvents such as methanol or ethanol and standardized to anthocyanin and polyphenol content
• Elderberry has been shown to reduce the duration of symptoms in viral and upper respiratory infections, likely due to the antiviral actions of its anthocyanins and the immune-supporting actions of its polysaccharides.
• Additional vitamin C is included to support phagocytic cells such as neutrophils, B cell and T cell differentiation, and increased inflammatory and metabolic demands during active infections

Childhood is a critical stage in immune system development as the body is first exposed to the many viruses, bacteria, and other microbes in our environment. This initial and subsequent exposure is unavoidable and very important for immune system development. However, steps can be taken to help ensure that immune tissues are robust enough to respond and adequately minimize symptoms in the affected child.

Sambucus nigra, more commonly known as elderberry, has traditionally been used to support the immune system and fight upper respiratory tract infections (URTIs) in adults and children. Today, there are numerous human clinical trials confirming the effectiveness of elderberry for this purpose. A randomized, double-blind, placebo-controlled study found that elderberry syrup was able to significantly reduce the duration of fever and illness in people aged 5 to 56 years with URTI. Another study tested the effects of elderberry on healthy people with confirmed influenza A or B when the intervention began within 48 hours of symptom onset. This trial showed that elderberry supplementation led to less medication use and faster resolution of symptoms such as nasal congestion, aches and pains, cough, and sleep disturbances compared to a placebo.

Elderberry positively affects the immune system and inhibits the proliferation of several strains of the influenza virus through multiple mechanisms of action. First, the anthocyanins present in elderberry extracts are able to bind directly to viruses and block their receptors, while also binding to neuraminidase, a key enzyme involved in the virus's spread. Second, elderberry polyphenols have been shown to increase microbial diversity through a prebiotic effect, specifically elevating levels of the beneficial bacterium Akkermansia muciniphila. Finally, the polysaccharide compounds contained in elderberry extract have been shown to stimulate the immune system.

When it comes to nutritional support for the immune system, vitamin C makes a strong case for being one of the most important compounds. While ascorbic acid is necessary for connective tissue formation, cardiovascular health, and even neurotransmitter production, it has been shown to support multiple immune functions. For example, vitamin C is stored in neutrophils and can enhance phagocytic action. It also enhances B-cell and T-cell differentiation through gene regulation. During active infections, vitamin C levels in the body drop due to increased inflammation and metabolic demands. Overall, vitamin C deficiency has been shown to impair immune function and make individuals more susceptible to infection, so it's not surprising that vitamin C supplementation can help both prevent and treat respiratory infections. Despite its importance for optimal immunity, the human body cannot synthesize vitamin C and dietary sources are needed to maintain adequate levels.

C Matrix Kids + Elderberry Chewable provides 250 mg of vitamin C and 25 mg of European black elderberry extract in a kid-friendly chewable format with a blueberry flavor. The elderberry is delivered in a proprietary and well-researched form known as Eldercraft®. Eldercraft® is processed without the use of solvents such as methanol or ethanol and is standardized for anthocyanin and polyphenol content.