Bio B Matrix HP

• A highly potent blend of B vitamins, in their metabolically active and highly bioavailable forms such as pyridoxal-5-phosphate (B6), methylcobalamin (B12) and 5-methyltetrahydrofolate (5-MTHF; B9)
• Contains benfotiamine, a fat-soluble version of vitamin B1, which has been shown to achieve higher peak blood levels, greater bioavailability (AUC), and better absorption in brain, muscle, liver, and kidney tissues
• Also contains inositol, a key molecule in improving the sensitivity of neurotransmitter and hormone receptors, and choline, a neurotrophic factor necessary for proper neurological development
• The full recommended daily dose is 3 capsules per day for optimal support

B vitamins are essential for optimal health because they are necessary cofactors for enzymatic reactions and most physiological functions. Unfortunately, many people's dietary intake does not match their body's needs, and various stressors and medications are well known to deplete various B vitamins.


Bio-B Matrix HP offers a solution by providing the most comprehensive blend of active and highly bioavailable B vitamins in the Cyto-Matrix range to effectively supplement the system.


Although B vitamins are traditionally considered for their ability to improve energy, mood, and cognition, the list of benefits and indications is extensive. For example, vitamins B6, B9, and B12 collectively help reduce homocysteine, a toxic metabolite linked to an increased risk of cardiovascular events, osteoporosis, and other chronic diseases. Many B vitamins are also necessary for the production of neurotransmitters such as serotonin and GABA, while in the liver, B vitamins play a crucial role in detoxification processes.

For these many reasons, B vitamin supplementation may be necessary in certain populations. The problem is that not all B vitamins are created equal, and each exists in many different forms, with varying rates of absorption and utilization in the body. For example, vitamin B6 in the form of pyridoxine HCl must first be activated in the liver to pyridoxal-5-phosphate. Folic acid must also be converted to 5-methyltetrahydrofolate (5-MTHF) to become metabolically active.


Bio-B Matrix HP includes all of these active forms for optimal absorption and utilization in the body and clinical results. However, the most unique form of B vitamin found in Bio-B Matrix HP is undoubtedly benfotiamine. Benfotiamine is a fat-soluble version of vitamin B1 that is much better absorbed than the more commonly supplemented thiamine HCl. Specifically, bioavailability studies have shown that benfotiamine results in approximately 5 times higher blood levels of B1 and 3.6 times greater bioavailability (based on AUC, area under the curve). Most importantly, benfotiamine allows for 5 times greater absorption in muscle tissue, 25 times greater absorption in brain tissue, and 10-40% greater incorporation in other organs such as the liver and kidneys. Clinical trials using benfotiamine have shown that it is able to protect nerves from damage, improve nerve conduction, and regulate blood sugar levels.

Bio-B Matrix HP offers a comprehensive blend of active and highly bioavailable B vitamins, including the highly effective and bioavailable form of vitamin B1, benfotiamine. Inositol and choline are added for their ability to improve receptor sensitivity and contribute to proper neurodevelopment, respectively.