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Berberine is a plant alkaloid with several powerful medicinal properties. It has traditionally been included as an active ingredient in extracts of goldenseal, Oregon grape, and barberry to provide broad-spectrum antimicrobial actions and digestive support. However, more recently, its isolation and powerful application in blood sugar control, insulin resistance, and cholesterol management have become evident.
Regarding berberine's antimicrobial properties, research has shown that it effectively combats bacteria, viruses, fungi, and parasites. It achieves these antimicrobial actions through multiple mechanisms, including inhibition of microbial growth, endotoxin formation, bacterial adhesion, and viral replication. This allows for a truly broad-spectrum approach for patients with dysbiosis, chronic infections, or exposure to multiple pathogens.
Berberine has a particularly beneficial effect on the digestive tract. Evidence has shown that berberine can effectively treat the symptoms of bacterial diarrhea and intestinal parasites. Additionally, berberine can improve the integrity of tight junctions in the digestive tract and, therefore, positively affect intestinal permeability. Finally, berberine can regulate gastrointestinal motility and increase the intestinal production of butyrate, a short-chain fatty acid that provides fuel and anti-inflammatory support in the colon.
Regarding metabolic function, research has discovered the wide application of berberine for insulin and blood sugar regulation. Double-blind, placebo-controlled studies using berberine in people with health conditions have shown that it can reduce fasting blood glucose, insulin resistance, hemoglobin A1c, triglycerides, total cholesterol, and LDL measurements. Remarkably, these effects are considered comparable to oral hypoglycemic medications. People with non-alcoholic fatty liver disease have also seen comparable improvements in lipids, body mass index, and insulin resistance, with significant improvements in liver fat content.
Cyto-Matrix Berberine contains 500 mg of Berberis aquifolium (Oregon grape extract) per capsule, standardized to 97% berberine to provide therapeutic support for healthy digestion, microbial balance, blood sugar regulation, and metabolic control.
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