Palmitoylethanolamide (PEA) is a long-chain fatty acid produced naturally by the body but also found in foods such as egg yolk, soybean, and sunflower oils. This molecule, studied for eighty years for its unique and varied health benefits, is now receiving special attention due to its crucial role in the endocannabinoid system (ECS). The ECS is a lipid communication network with critical physiological functions. It is a signaling network that communicates with other systems in the body, helping to regulate them. PEA is an endocannabinoid produced locally by cells and accumulates in tissues following any injury, physical stress, or pain.
By inhibiting the activation of mast cells that cause further inflammation (such as histamine release), PEA acts as a potent anti-inflammatory agent. This unique molecule has other direct and indirect mechanisms of action; it even enhances the action of other endocannabinoids through its “entourage effect.” The PEA molecule has been clinically demonstrated for pain relief in knee osteoarthritis as well as for reducing symptoms of low back pain. This potent small molecule is well tolerated by athletes, children, and the elderly.
AOR is leading the way in transforming the impressive and evolving research on the positive effects of PEA on the human endocannabinoid system to provide its valued customers with a safe therapeutic formula to combat chronic pain and systemic inflammation. AOR's Active PEA is produced in Italy and derived from environmentally sustainable Malaysian palm oil, purified and responsibly processed for optimal bioavailability.