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L-carnitine is an amino acid classically known for its role in transporting fatty acids into the mitochondria for energy production. Acetyl L-carnitine (ALC) is the acetylated form of L-carnitine. It is the only form shown to cross the blood-brain barrier. This ability to penetrate the central nervous system and its ability to upregulate acetylcholine production offer unique benefits for the brain and cognitive function.
CLA has also demonstrated powerful protective effects on the peripheral nervous system. Clinical trials using CLA in cases of nerve damage following antiretroviral drugs have all yielded positive results. Improvements in pain, vibration perception, nerve function, and nerve regeneration have been observed.
Other clinical indications for ALC supplementation include poor sperm motility, male infertility, Peyronie's disease, cerebral ischemia, and insulin resistance. Studies of ALC have been shown to positively affect each of these conditions when properly supplemented.
The mechanisms underlying the benefits of CLA appear to be multifactorial. CLA has cholinergic action in the body and is essential for transporting fatty acids into the mitochondria for energy production. CLA also stabilizes cell membranes, increases nerve growth factor levels, and inhibits excitotoxicity in the nervous system.
Acetyl-L-Carnitine provides 500 mg of pure acetyl-L-carnitine per capsule to support energy production and mitochondrial function in a wide variety of clinical scenarios. By providing the acetylated form of L-Carnitine, Acetyl L-Carnitine ensures delivery and protection to the central and peripheral nervous system.
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